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Pharmaceutical corporations that run plasma centers pay American donors between $30 and $70 per donation. You can donate up to twice per week or 104 times per year.

Under the most aggressive scenario, an individual could collect $70 x 104, or $7,280 per year. Donors receive payment through prepaid debit cards.

The study’s authors estimate that between 2.54 million and 3.7 million US adults provided 64% of the global plasma market in 2019. More than 1 million US donors sell plasma 20 or more times per year at a compensation rate of $30 to $50 per collection. These donors earn an annual income that ranges from $630 to $5,200.

Interestingly, the plasma centers do not report donor payments to the IRS because each one is below the $600 threshold. But donors should report earnings greater than $400 as self-employment income.